PRODUCTS
MEROFLEX 1:1
Meroflex 1:1
Cannabis sativa L. extract / Oral drops solution.
Each 100 mL contains: Cannabis sativa extract 9.0 g (*) Excipients qs. (*) equivalent to 2.7 g Cannabidiol (CBD) and 2.5 g Tetrahydrocannabinol (THC).
FORMULA
Each 100 mL contains:
Cannabis sativa extract 9.0 g (*)
Excipients qs. (*) equivalent to 2.7 g Cannabidiol (CBD) and 2.5 g Tetrahydrocannabinol (THC).
Use in adults under medical supervision. Read the entire package leaflet carefully before you start using this medicine.
– If in doubt, consult your doctor or pharmacist.
– If you experience side effects, consult your doctor or pharmacist.
INDICATIONS
The use of this product, dosage indications and monitoring should be carried out ONLY under medical prescription. It is advisable to start gradually with daily intakes of 3 drops and monitor the possible effects, gradually increasing up to a suggested maximum of 35 drops per day divided into two intakes (e.g. morning and evening), always monitored by the treating medical professional.
FORM OF ADMINISTRATION
Oral use.
Fatty foods may increase the levels of available cannabinoids, so it is recommended that administration be done consistently, with or without food, as defined by the treating physician.
PHARMACOLOGICAL ACTION
Among the more than 460 active compounds present in the species, cannabinoids stand out, of which more than 100 types have been reported, acting on the endogenous cannabinoid system (ECS). This neuromodulatory system is linked to several vital functions and is responsible for regulating and modulating different physiological pathways. The most abundant cannabinoids include tetrahydrocannabinol (THC), tetrahydrocannabinolic acid, cannabinol and cannabidiol (CBD), for which anticonvulsant, antitumour, anti-inflammatory and other activities have been reported. The combination of CBD and THC in the ratio contained in this product can produce an improvement in symptoms related to stiffness (spasticity), especially in Multiple Sclerosis (MS).
CONTRAINDICATIONS
– Psychotic disorders.
– Patients with psychological problems.
– Heart problems: cardiac arrhythmias, coronary insufficiency or patients who have had angina pectoris or a heart attack.
– People who have to use machinery or have to drive: in this case, it is recommended, if the product has been consumed, to wait at least four hours before resuming activities.
Prolonged use may cause some of the following adverse effects: drowsiness, fatigue, gastrointestinal disturbances and irritability.
INTERACTIONS
– Selective serotonin reuptake inhibitors (SSRIs) antidepressants: THC may increase the effect of fluoxetine.
– Tricyclic antidepressants: THC may increase the side effects of amitriptyline, which include tachycardia, hypertension and sedation.
– Nonsteroidal anti-inflammatory drugs: Indomethacin and acetylsalicylic acid reduce the effects of THC.
– Barbiturates: They increase the depressant effects of THC and also increase the tachycardia caused by THC.
– Benzodiazepines: can increase the depression of the nervous system and also of the respiratory system.
– Beta-blockers: Reduce the tachycardia associated with THC.
– Ethanol (alcohol): may increase nervous system impairment.
– Opiates: increase sedation and analgesia.
– Theophylline: Cannabinoids increase theophylline catabolism.
– Anticholinergics: Atropine and scopolamine may increase the tachycardia produced by THC.
– Disulfiram: THC interacts with disulfiram, producing a very unpleasant reaction for the patient.
SIDE EFFECTS
After consuming the product, the person may have a feeling of euphoria that gradually changes to a feeling of contentment, calm and tranquillity. Other effects may include: relaxation, fits of laughter, appetite, great sensitivity to music and colours, change of sense of space and time, and sluggishness. A lack of reaction may also occur, especially during the first hours after use. The first four hours after ingestion of the product should be taken into account.
The changed perception can lead to feelings of fear, panic and confusion.
If you experience any undesirable effects, consult your doctor.
In case of PREGNANCY and BREASTFEEDING
The Meroflex 1:1’s use is not recommended during pregnancy and lactation, as cannabinoid compounds may reach the foetus and may also be excreted in breast milk.
CONSERVATION
Keep out of the sight and reach of children. Do not use this medicine after the expiry date which is stated on the pack. Store the product in an upright position at a temperature below 30 °C.
Blue glass dropper bottle of 30 mL capacity. Composition per 100 mL: Diluted extract containing Cannabidiol (CBD): 2.7 g and Delta-9-tetrahydrocannabinol (THC): 2.5 g
Oily vehicle q.s. 100 mL.
Manufacturer
BUREY S.A.
MSP Registration
Camino Saravia y Ruta 8, Parque Tecnológico
Technological and Scientific Park of Pando Canelones, Uruguay.
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GrüneLabs is a global Phytopharmaceutical company with operations in Uruguay, and Portugal.
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